The round was known as "Pick Your Pony" for the first three seasons and "Pick Your Brain" in the final two seasons.Each question goes to an individual contestant, who must decide whether their "brain/pony" got the question right or wrong.After getting it incorrect, Nicotero walked up to the camera and said to the contestant "I bet you thought she would get this right!
Beginning in season two and continuing for the remainder of the series, the contestants stood behind a desk for the whole show and recorded their answers by way of pushing buttons." After some thought, the savant answered "Beige." Another notable example was an elderly woman who claimed to be a nurse and, when asked what HMO meant, she got it confused with the premium television channel, HBO.Occasionally Nicotero, when asking the savant, would break the fourth wall, such as when a savant who was in the US Navy was asked to define "league" as in 20,000 Leagues Under the Sea.Before the game actually starts, two studio contestants are introduced, as well as three "street savants", whose interviews were pre-recorded.A question is posed, and the studio contestants must choose which of the three "savants" gave the correct answer. Three questions are asked in this round, and sometimes two "savants" will have answered a question correctly.
The "right" reference is indicated in green; the "wrong" reference in red.