On February 28, 2006, Maron began hosting a nighttime radio program with Jim Earl as sidekick for KTLK Progressive Talk 1150AM in Los Angeles called The Marc Maron Show from pm until midnight PST.
His last Morning Sedition broadcast was on December 16, 2005, and the show was discontinued shortly thereafter.
In January 2009, a collaboration with Sam Seder which had begun in September 2007 as a weekly hour-long video webcast became Breakroom Live with Maron & Seder, produced by Air America.
Until its cancellation in July 2009, the show was webcast live weekdays at 3 pm Eastern, with episodes archived for later viewing as well.
As 2005 came to a end, it became known that Maron's contract would not be renewed on its December 1, 2005, end date because of problems with then Air America executive Danny Goldberg.
Goldberg reportedly did not "get" the comedy or agree with the satiric and often angry tone set by Maron and other writers (Jim Earl and Kent Jones) for a morning drive-time show.
The show was unique in the Air America lineup in its heavy reliance on both live and preproduced sketch comedy, utilizing the talents of staff writers as well as the on-air hosts.