The woman who had been trapped was taken to Kings Hospital along with two other passengers while the man was transported to St George’s alongside three others.
Other passengers were taken to St Thomas’ Hospital.
“We used ladders to get some of the people out and in the case of the final two passengers trapped on the top deck crews had to shore up the upper floor which had started to collapse before using specialist cutting gear to release them.
“The man and woman were then lowered to the ground on a stretcher by firefighters on a turntable ladder.” Four fire engines attended with police, the London Ambulance Service and an air ambulance.
Two uniformed police officers were travelling on the bus and were injured.
A paediatrician who arrived on the scene shortly after the crash, said she treated people for shock, cuts and bruises and facial injuries.
A man with a bloodied head was seen being put on to an ambulance and emergency crews were using a cherry picker to gain access to the back of the bus.
Ambulance crews described 25 people as “walking wounded”, five more suffered more serious head and leg wounds while the pair who had been trapped had severe leg injuries.
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"There will be a thorough investigation into this incident as a matter of urgency." Fire crews used ladders to remove people and seats from the top desk of the back of the bus.
Clive Robinson, fire station manager who was at the scene, said: “This was a particularly nasty crash and our crews worked extremely hard in very challenging circumstances to get the passengers off the bus.
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